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| Francis GAINES Sr. (ABT 1704 - 1774) | Res: Culpeper and KQ Cos. VA |
| Francis Marion GAINES (ABT 1810 - ____) | Res: VA and Simpson Co. KY |
| Francis Pendleton GAINES (Prof.) (21 Apr 1892 - 31 Dec 1963) | Res: SC; NC; Lexington, VA |
| Francis Pendleton GAINES Jr. (ABT 1814 - ____) | Res: Scott Co. KY |
| Francis Pendleton GAINES Sr. (ABT 1786 - 1820) | Res: Culpeper Co.VA and Lincoln Co. KY |
| Francis Strother GAINES (ABT 1810 - ____) | Res: AL |
| Francis Thornton GAINES (1 Nov 1789 - 1837) | Res: Stokes Co. NC and TX |
| Garth A. GAINES (1843 - 1919) | Res: Lincoln and McCracken Co. KY |
| George GAINES (ABT 1675 - ____) | Res: Richmond Co. VA |
| George GAINES (ABT 1730 - ____) | Res: Caroline Co. VA |
| George GAINES (20 Oct 1766 - 28 Jun 1839) | Res: Orange and Madison Cos. VA and Boone Co. KY |
| George GAINES (1812 - ____) | Res: Pickens, SC & Montgomery Co. NC |
| George Dinsmoor GAINES (ABT 1730 - ____) | Res: SC |
| George Shipp GAINES (8 Dec 1828 - 22 Dec 1910) | Res: Greene and Walker Cos. AL |
| George Strother GAINES (1 May 1784 - 21 Jan 1873) | Res: Culpeper Co. VA and 1794 To TN and 1804 To Washington Co.MS Terr. (Adams Co. MS) |
| George Washington GAINES (1787 - 1862) | Res: Surry Co. NC |
| George Washington GAINES M.D. (Dr.) (1840 - ____) | Res: of Simpson Co. KY |
| George Whitefield GAINES (24 Dec 1865 - 20 May 1929) | Res: Central; Belton, SC |
| Gideon GAINES (ABT 1800 - ____) | Res: TN |
| H. E. GAINES (ABT 1837 - ____) | Res: Allen Co. KY |
| Hannah GAINES (24 Nov 1764 - ____) | Res: of Culpeper now Madison Co. VA |
| Harriet P. GAINES (17 Jan 1826 - ____) | Res: Central, SC |
| Harry GAINES of "Greenway" (Maj.) (ABT 1720 - 1767) | Res: King William Co. VA |
| Harry GAINES of "Providence" (1746 - ABT 1787) | Res: King and Queen Co. VA |
| Harry Edmund GAINES (____ - ____) | |
| Hattie GAINES (ABT 1870 - ____) | Res: Cambria Co. PA |
| Helen Pendleton GAINES (1814 - ____) | Res: Pickens, SC & Montgomery Co. NC |
| Henry GAINES (1692 - 5 Jun 1734) | Res: of Middlesex and of Culpeper now Madison Co. VA |
| Henry GAINES (1731 - 1796) | Res: K&Q Co. VA & Mt. Gallagher area Laurens Co. SC |
| Henry GAINES (ABT 1733 - 1811) | Res: Culpeper and Madison Cos. VA |
| Henry GAINES (Rev.) (1737 - 25 Jul 1830) | Res: Culpeper and Middlesex, Cos.VA and abt 1797 Abbeville and Pickens Cos. SC |
| Henry GAINES (11 Apr 1755 - 19 Dec 1778) | Res: of Culpeper now Madison Co. VA |
| Henry GAINES of "Woodlawn" (ABT 1770 - 1829) | Res: of Gloucester and KandQ Co. VA |
| Henry "Harry" GAINES (ABT 1780 - ____) | |
| Henry Benjamin GAINES (29 Aug 1853 - 30 Mar 1911) | Res: Autauga and Walker Co. AL and Brown Co. TX |
| Henry George GAINES (Jun 1831 - 1909) | Res: Lauderdale Co. TN |
| Henry Goodloe GAINES (ABT 1791 - ____) | Res: Shenandoah and Rockingham Cos. VA |
| Henry Lawrence GAINES (1827 - ____) | Res: Demopolis, AL |
| Henry Lewis GAINES (2 Jul 1818 - 20 Nov 1854) | Res: Pickens, SC |
| Henry Mayo GAINES (Rev.) (1769 - AFT 1833) | Res: VA; Pickins Co. SC; TN; TX |
| Henry Mortimer GAINES (ABT 1805 - ____) | |
| Henry Pendleton GAINES (30 Mar 1779 - 1 Jan 1865) | Res: Stokes Co. NC and Walker Co. AL |
| Henry Pendleton GAINES (3 Mar 1792 - ____) | Res: Pickens Co. SC |
| Henry Pendleton GAINES (8 Oct 1798 - 7 Nov 1860) | Res: Culpeper Co. VA and and Montgomery Co. NC and Henry Co. TN |
| Herndon GAINES (ABT 1800 - ____) | Res: King and Queen Co. VA |
| Hiram GAINES (ABT 1780 - by 1835) | Res: Abbeville Dist. SC |
| Humphrey GAINES (25 Nov 1718 - 16 Aug 1779) | Res: of Culpeper now Madison Co. VA |
| Humphrey GAINES (ABT 1760 - ____) | Res: VA and SC |
| Ira Broadus GAINES C.S.A. (1832 - Feb 1863) | Res: TN and Stoddard Co. MO |
| Ira Mayo GAINES (21 Jul 1801 - 29 May 1861) | Res: Abbeville Co. SC and Lauderdale Co. TN and Marshall Co. MS |
| Ira Robert GAINES (1840 - ____) | |
| Irene Mary GAINES (28 Apr 1860 - 7 Aug 1955) | Res: Walker Co. AL and Brown Co. TX |
| Isaac Newton GAINES (10 Mar 1871 - ____) | Res: Newport, Page Co. VA; Cambria Co. PA |
| Isabella GAINES (1746 - ____) | Res: Culpeper Co. VA |
| Isabella GAINES (1759 - 1787) | Res: Culpeper Co.VA; NC |
| Isabella GAINES (1787 - 27 Oct 1871) | Res: Charles Co. MD & Abbeville, SC |
| J. N. GAINES (ABT 1845 - ____) | Res: Allen Co. KY |
| James GAINES (1620 - ABT 1705) | Res: Wales and Rappahannock, VA |
| James GAINES (14 Oct 1760 - 4 Dec 1854) | Res: VA & Pickens, SC & Montgomery Co. NC |
| James GAINES (ABT 1780 - ____) | Res: Culpeper Co. VA |
| James GAINES (ABT 1780 - ____) | Res: Culpeper Co.VA |
| James GAINES (ABT 1790 - ____) | |
| James GAINES (1793 - ____) | Res: VA; Newberry Co. SC |
| James GAINES (Rev.) (9 Mar 1799 - 10 Sep 1868) | Res: Pickens Co. SC and TN and 1849 Lawrence Co. AL and Tishomingo Co. MS |
| James GAINES (ABT 1800 - ____) | Res: VA or Pickens Co. SC? |
| James GAINES (ABT 1830 - ____) | Res: GA |
| James GAINES I (18 Jan 1719 - 10 Mar 1786) | Res: Orange and Culpeper Cos. VA |
| James GAINES II (1739 - 25 Nov 1788) | Res: Culpeper; Orange Cos.VA |
| James GAINES III (ABT 1770 - ____) | Res: of Culpeper and Orange Cos. VA |
| James Edward GAINES (13 Oct 1810 - ABT 1846) | Res: Lincoln Co. KY |
| James Foster GAINES (20 Jul 1805 - 10 Sep 1836) | Res: Manassus Gap, VA and Parks, Scott, AR |
| James Francis GAINES (27 Sep 1812 - Apr 1881) | Res: VA and Gallatin, TN |
| James H. GAINES (1796 - AFT 1843) | Res: Charlotte Co. VA |
| James H. GAINES (15 Oct 1799 - 31 Jan 1888) | Res: VA and Cumberland Co. KY and Henry Co. MO |
| James Lowe GAINES (ABT 1795 - 1863) | Res: VA and Pickens, SC and Montgomery Co. NC |
| James Pendleton GAINES (7 Jul 1824 - 2 Jan 1890) | Res: Montgomery Co. NC; Noxubee Co. MS |
| James Strother GAINES (1770 - 20 Oct 1823) | Res: Culpeper Co. VA and Stokes Co. NC and Cahawba, Dallas Co. AL |
| James Strother GAINES (27 Mar 1823 - 15 Oct 1853) | Res: of Sullivan Co. TN |
| James Taylor GAINES (Capt.) (ABT 1742 - bet. 1829-1834) | Res: Culpeper Co. VA; Surry Co.NC; 1788 Sullivan Co. TN |
| James Taylor GAINES Jr. (1793 - 1883) | Res: Sullivan Co. TN |
| James William GAINES (ABT 1810 - ____) | Res: VA and Simpson Co. KY |
| Jane "Jennie" GAINES (ABT 1775 - 1849) | Res: Culpeper Co. VA and Pickens Co. SC |
| Janie Robbins GAINES (25 Jun 1868 - 6 Dec 1936) | Res: Central; Greenville, SC |
| Jemima GAINES (ABT 1760 - ABT 1831) | Res: Culpeper Co. VA & KY |
| Jessie Tucker GAINES (23 Mar 1845 - ____) | |
| Joanna N. GAINES (____ - bet. 1828-1834) | Res: Abbeville Dist. SC |
| John GAINES (1680 - 1718) | Res: of Essex Co. VA |
| John GAINES (1712 - ____) | Res: Culpeper Co. VA |
| John GAINES (1787 - 30 Sep 1848) | Res: King and Queen Co. VA |
| John GAINES (ABT 1790 - ____) | Res: GA |
| John GAINES (ABT 1793 - ____) | Res: Shenandoah and Rockingham Cos. VA |
| John GAINES (ABT 1800 - ____) | Res: Orange Co. VA and Abbeville and Laurens Dist. SC |
| John GAINES (25 Dec 1804 - 16 May 1870) | Res: VA and Burlington, Boone Co. KY |
| John GAINES (ABT 1860 - ____) | Res: MO |
| John Cook GAINES (1768 - ____) | Res: Culpeper Co. VA |
| John F. GAINES (ABT 1791 - ____) | Res: Charlotte Co. VA |
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