From Landmarks of Monroe County, NY
by William F. Peck (1895)
Part III, p. 95 - 96

Otis, Dr. Charles F., was born in Rochester in 1860, a son of Dr. Clark Otis of Livingston County, whose father was Matson Otis, a Warsaw merchant. The mother of Charles F. was Mary Ann Shedd, daughter of Philander Shedd, and sister of K. P. Shedd. The ancestors of the Otis family were prominent in New England in the early history of the country and were among the early colonists. In 1859 Mr. Matson and Clark Otis went to Rochester and engaged in photography. Eight years later found Clark Otis in Cuba, where he was burned out. He had studied medicine, and next began practice in Byron. After this he went west, and in 1876 returned to Honeoye Falls. In 1881 he removed to Penn Yan, and was succeeded in his practice by Charles F., then a young man of twenty-one who had just taken his diploma from the Hahnemann Medical College of Chicago, and the latter has had a very successful practice. He married Mary A. Hutchinson, a niece of William Downey, and has two sons, William Kirk and Charles Francis, Jr. Mrs. Otis has carried on a flourishing business in a millinery store.