| Surname | Data | Member # |
| QUACKENBUSH | Montgomery Co., NY | G141 |
| QUICK | Tioga & Broome Co., NY | F201 |
| QUICK | CT; NY; MI | M523 |
| QUIGG | Oswego, Oneida and Onondaga Co., NY | C476 |
| RALPH | Canton, St. Lawrence Co., NY | K184 |
| RAMSEY | Allegany Co., NY | B545 |
| RANDALL | Tioga Co., NY; Bradford Co., PA | C459 |
| RANDALL | Broome & Chenango Co., NY | T159 |
| RANDALL | Albany & Onondaga Co., NY | W396 |
| RANGER | Brockville, Ontario Canada; Northern NY; Town of Salina, Onondaga Co., NY | S548 |
| RANNING / RANNINGS | NY | B563 |
| RECKNER | Troy, NY | P195 |
| REDDY / READY | Orange, Cayuga, Tompkins & Stuben Co., NY | B512 |
| REED | Manlius, NY | S616 |
| REID | Syracuse & Albany, NY | R270 |
| REYNOLDS | Dutchess, Saratoga & Otsego Co., NY | C384 |
| REYNOLDS | Madison, Ontario & Cattaraugus Co., NY; Racine Co., WI | H398 |
| REYNOLDS | RI; Wayne Co., NY | S225 |
| RHODES | Jefferson Co., NY | W209 |
| RICHARDSON | St. Lawrence Co., NY; Canada | D146 |
| RICHARDSON | Madison Co., NY | E081 |
| RICHARDSON | Chautauqua Co., NY; MN | S357 |
| RICHARDSON | Medway, MA; Middleton, VT; Oswego Co., NY | B462 |
| RICKARD | Middleborough, MA; Schutesbury, MA; Truxton/ Cortland, Cortland Co., NY | C193 |
| RIDER | Madison, Chenango & Dutchess Co., NY | E081 |
| RIDER / RYDER | MA; NY | H341 |
| RIGHTMYER | Openheim, NY | J069 |
| RINGER | Erie Co., NY; Prussia, Germany | M505 |
| RIVERIN | France; Quebec, Canada | J135 |
| ROBINSON | Livingston & Cattaraugus Co., NY | S508 |
| ROGERS | Oswego Co., Cayuga Co. & Washington Co., NY | C464 |
| ROGERS | Orleans & Monroe Co., NY | L226 |
| ROGERS | VT; Otsego Co., NY; Fulton, NY | B449 |
| ROOD | England; Norwich, Saybrook & Lisbon, New London, CT; Sturbridge, Worcester Co., MA; Monson/Amherst, MA.; Durham, Greene Co., NY; Bristol/Broome, Schoharie Co., NY; Plainfield/Durham, Otsego Co., NY; Cortland, Cortland Co., NY | S534 |
| ROOT | Madison & Oneida Co., NY | C465 |
| ROOT | Otsego Co., NY | N106 |
| ROOT | Tolland Co., CT; Delaware Co., NY | C372 |
| ROOT | Chenango & Columbia & Monroe Co., NY | T134 |
| ROSE / ROOS | Ontario; NJ; Seneca & Rockland Co., NY | T153 |
| ROSE | Stony Point, Rockland Co., NY | N097 |
| RUBIN | Elizabethgrad, Russia; Kings Co., NY | T154 |
| RUSHTON | St. Lawrence Co., NY | R299 |
| RUST | Onondaga Co., NY | P270 |
| RYAN | Syracuse, Onondaga Co., NY | A158 |
| SADDINGTON | Kettering, Northamptonshire, England; Oswego Co., NY | T154 |
| SAMPSON | Syracuse & Fulton, Onondaga Co., NY | W373 |
| SCANLIN | Oneida & Lewis Co., NY | C325 |
| SCHAEFFER | Albany Co., NY; Lehigh & Northampton Co., PA | T153 |
| SCHEIBEL | Syracuse, Onondaga Co., NY | W429 |
| SCHERMERHORN | Schodak, Poland & North Gage, NY | B260 |
| SCHERMERHORN | Schenectady, NY; Truxton, Cortland Co., NY | C193 |
| SCHERMERHORN | Dutchess, Otsego & Chenango Co., NY | C435 |
| SCHIESSER | Switzerland; Town of Salina, Onondaga Co., NY | S548 |
| SCHMIDT | Syracuse, Onondaga Co., NY | A158 |
| SCHMIDT | Prussia, Germany; Onondaga Co., NY | G141 |
| SCHMITTAU / SCHMITAU | Stone Arabia, NY; TN | B574 |
| SCHNECKENBURGER | Germany; Livingston & Wyoming Co., NY | B431 |
| SCHROLL | Germany; Rochester, NY | S508 |
| SCOFIELD | Hadley, Saratoga Co., NY; Kingsbury, Washington Co., NY | D146 |
| SCOTT | Little Britain, Orange Co., NY | B512 |
| SCOTT | Chemung & Chautauqua Co., NY | E081 |
| SCOTT | Otsego Co., NY; Stockton, Chautauqua Co., NY; MN; WA | S357 |
| SCOVEL | Hartland, Hartford Co., CT; E . Bloomfield, Ontario Co., NY; Parma, Cuyahoga Co., OH | S526 |
| SCUTT | Wayne & Columbia Co., NY | S178 |
| SEAMANS | Swansea, MA; Foster, RI; Otsego Co., Herkimer Co., & Oswego Co., NY | B462 |
| SEAMONS | Herkimer Co., NY; RI | B197 |
| SEARLE, Harlow | NY | S600 |
| SEELEY | Pittstown & Skaneateles & Marcellus, NY | W224 |
| SEELY | Tioga, Delaware, Tompkins, Chemung, Broome, Schoharie, Ulster, Onondaga, Genesee, Chenango, Green Monroe, Otsego & Ontario Co., NY | B175 |
| SEGOVIS | Carthage & Watertown, NY | P221 |
| SEIBERT | Hesse Darmstadt, Germany; Auburn & Sennett, Cayuga Co., NY; Syracuse, Onondaga Co., NY | W373 |
| SELDEN | Oneida Co., NY | T170 |
| SESSLER | Germany; Onondaga Co., NY | S548 |
| SEYMOUR | CT; NY; MI | M523 |
| SHAMPANG | Oswego & Chenango Co., NY | V059 |
| SHANNON | Schenectady, NY; Canada | D146 |
| SHANNON | Syracuse, NY; Ireland | F218 |
| SHAVER | Cayuga, Ulster & Delaware Co., NY | E107 |
| SHAVER | Niagara Co., NY | E110 |
| SHAW | Chenango & Madison Co., NY | D257 |
| SHAW | Chenango & Herkimer Co., NY; Utica, NY | D257 |
| SHEPARD | CT; NY; MI | M523 |
| SHERMAN | Oswego, Onondaga & Herkimer Co., NY | R299 |
| SHERWOOD | Onondaga, Saratoga & Orange Co., NY | H412 |
| SHIRLEY | Ontario & Rockland Dutchess & Seneca Co., NY | T153 |
| SHUTE | New England; Westchester Co., NY | S534 |
| SIEGEL | Bialystok, Russia; Kings Co., NY | T154 |
| SIMOND | Washington Co., NY | M508 |
| SINGER | PA; Town Fayette, Seneca Co., NY; Niagara Co., NY | S225 |
| SKINNER | Camden, Oneida Co., NY | D224 |
| SKINNER | Herkimer Co., NY | R192 |
| SLAUTER / SLATER | Tioga, Delaware, Tompkins, Chemung, Broome, Schoharie, Ulster, Onondaga, Genesee, Chenango, Green Monroe, Otsego & Ontario Co., NY | B175 |
| SMALL | Deansboro, NY; Marshall, Oneida Co., NY | H394 |
| SMITH | Onondaga & Oswego Co., NY | C409 |
| SMITH | NY | G229 |
| SMITH | CT; NY; MI | M523 |
| SMITH | RI; Duchess & Cortland Co., NY | S534 |
| SMITH | Oneida & Oswego Co., NY | T163 |
| SNELL | Afton, Chenango Co., NY | B569 |
| SNOW | Madison, Cortland & Onondaga Co., NY | W382 |
| SNYDER | Canada; Bombay & Moira, Franklin Co., NY | L181 |
| SOCHIA/SAUCIER | Canada; Brasher Falls, NY; Onondaga Co., NY | R213 |
| SOPER | Saratoga Co., NY | W429 |
| SOPER; SURPRENANT; SUPERNAUT; SUPRENAUT | Keeseville, NY; Vermont; Canada | M518 |
| SOUTHWORTH | Perrysburg, Cattaraugus Co., NY | B548 |
| SPENCER | Calvert Co., MD | B405 |
| SPONBURGH | Herkimer & Otsego Co., NY; OH | C384 |
| SPONENBURGH | Otsego Co., NY; Lorain Co., OH; Montgomery Co., NY | C384 |
| SPRAGUE | Chenango & Monroe Co., NY | T134 |
| SPRINGER | Albany, Rensselaer, Herkimer & Otsego Co., NY | N106 |
| STAFFORD | NY | S569 |
| STAHL | Lehigh, Perry, Union & Northumberland Co., PA; Seneca Co., NY | S225 |
| STALLKNECHT | NY; MI | S597 |
| STANTON | NY; Washington Co., OH; Ionia Co., MI | C462 |
| STEEL(E) | Jefferson Co., NY; VT | G141 |
| STEFFY | Livingston Co., NY | C459 |
| STEITLER | Germany; Wayne Co., NY | S225 |
| STERLING | Amsterdam, NY; Wilton, CT | R270 |
| STEVENS | Cayuga Co., NY | B474 |
| STEWART | Kemptville, Ontario, Canada; Town Lorraine, Jefferson Co., NY | L181 |
| STICKLE | Columbia Co., NY | W297 |
| STITT | Hartford, CT; IL; London, England | D305 |
| STODDARD | Jefferson & Lewis Co., NY | C325 |
| STODDARD | Coventryville & Coventry, Chenango Co., NY | R300 |
| STOEL | Madison Co., NY; NH | H398 |
| STORTO | Onondaga Co., NY | C476 |
| STRAIN | Otsego Co., NY | C384 |
| STRICKLAND | Chenango & Stuben Co., NY | M508 |
| SUITS | Montgomery & Fulton Co., NY | J148 |
| SULLIVAN | Albany & Schenectady Co., NY | F195 |
| SULLIVAN | Fulton, NY; Ireland | F218 |
| SURPRENANT; SUPERNAUT; SUPRENAUT; SOPER | Keeseville, NY; Vermont; Canada | M518 |
| SWARTWOUT | Dutchess Co., NY, Fishkill, NY | B175 |
| SWEET | Coventry, RI; CT; W. Stockbridge, MA; Albany, Chenango & Broome Co., NY | B512 |
| SWINGLE | Orange Co., NY | A158 |
| SZELACHA | Rzeszow, Poland; Galicia, Poland; Syracuse, NY | C415 |