Kentucky:  A History of the State, Battle, Perrin, Kniffin 2nd ed., 1885
Crittenden Co.

W.S. CAIN, M.D., was born January 26, 1827, in Crittenden County, and is a
son of Charles and Ellen (Stewart) Cain.  Subject's paternal grandfather 
was William Cain.  He was born in South Carolina, and shortly after the
Revolutionary war moved to Georgia, where he lived until 1806, when he
immigrated to Kentucky, and settled in what is now Crittenden County,
near where subject still lives.  He died in 1842 or 1843.  William
Stewart, subject's maternal grandfather, was a native of South Carolina
also.  He moved to Kentucky in 1806 and settled near Piny Creek, in
Crittenden County; he afterward moved to Illinois, in which State his
death occurred in 1856.  He was a soldier in the Revolution and received
a severe wound at the battle of Camden.  Charles Cain was born in 
Georgia in 1796, and was but ten years old when his parents moved to
Kentucky.  He was a resident of Crittenden County for sixty-five years, 
dying here in 1871.  Mrs. Cain was born in South Carolina, and died in
Crittenden County in 1872, at the age of seventy-two years.  Subject is
the second of a family of seven children born to Charles and Ellen Cain.
At the age of twenty-two years he engaged in teaching school, which he
followed for two years.  In 1851 he commenced the study of medicine with
Dr. Gillam, of Marion, in whose office he remained two years, and at the
end of that time commenced the practice of his profession at Bell's Mines,
where he remained until 1855.  In the latter year he came to Marion and
effected a co-partnership with Dr. J.A. Hodge, which was continued one
year.  In 1857 Dr. Cain entered the St. Louis Medical College, from
which he graduated in March of the following year.  After leaving 
college he returned to Marion, where he practiced his profession until
1877, at which time he moved to Illinois, locating at Cave-In-Rock,
where he remained two years.  From Cave-In-Rock he came to Weston, this
county, and in 1882 moved to his present location five miles northeast of
Marion, where he has since practiced his profession.  Dr. Cain married
June 24, 1859, to Mrs. Mary A. Bence, daughter of Marcus Twitchell, of
Ohio.  Mrs. Cain died July 29, 1870, at the age of forty-two years.  The
Doctor next married, December 31, 1870, Mrs. Susan A. Peck, daughter of
John M. and Mary E. (Jackson) Carter, of Henderson County, Ky.  Three
children have been born to Dr. and Mrs. Cain:  Maggie D., Dixie and 
Kittie S.  By previous marriage Mrs. Cain had one child, who has since
been adopted by the doctor; its name is William Walter Cain.

Cain Stewart Gillam Hodge Bence Twitchell Peck Jackson Carter
= 
SC GA IL OH Henderson-KY

http://www.rootsweb.com/~kygenweb/kybiog/crittenden/cain.ws.txt