On 7 March 1769, he sold the plantation inherited from his father to Richard Bristow, (9 Middlesex Deeds 57) and moved to Prince Edward County. There he bought 100 acres from Andrew Wallace on 18 June 1770 described as being "on both sides of Falling Creek of the north side of Buffalo River". (4 PE Deeds 146). On 5 Nov 1771 he purchased 245 acres from Dabney Pettus described as "being on the north side of Buffalo River beginning at Wallace's corner in Bauldwin line." (4 PE Deeds 237).
Lodowick conveyed 90 acres of his boundary to Philemon Bird (a brother-in-law who marred Mary Lee) 20 July 1772 (5 PE Deeds 197). He resided in Prince Edwrd until 1776 when he disposed of his property by three separate conveyances, all dated 19 February. Williamson Bird purchased 40 acres (5 PE Deeds 527), Philemon Bird 40 acres (6 PE Deeds 76), and John Holecombe 171 acres "being the place the said Tuggle now lives on." (6 PE Deeds 134).

Lodowick and Dorothy at once moved to Pittsylvania County and on 28 April 1776 bought 400 acres on Turkey Cock Creek, "including the mill" from George Jefferson, (5 Pitt.Deeds 67). A land grant for 175 acres "on the south side of Pigg River, beginning at Francis Kerby's Corner Beech" was issued to him 1 Sept. 1780, (E Va. Land Grants 523). On 2 April 1784 he had surveyed a tract containing 296 acres "on Pigg River and Snow Creek beginning at his corner" and calling for Jefferson's line on the north and Peter Finney's line on the south (2 Va. Land Grants 61). Lodowick obtained a Land Officers Treasury Warrant on 9 June 1783 for 250 acres which was surveyed 20 April 1785, described as being on the branches of Turkey Cock Creek and "beginning at the said Tuggle's corner maple" (16 Va. Land Grants 82). He had also purchased shortly after arriving in Pittsylvania, on 26 Sept 1776, a bounty of 100 acres from Garrett, (4 PE Deeds 245).

Lodowick was a Lieutenant in the Pittsylvania Militia during the Revolutionary War. An order under date of 23 Oct 1777 appears at 4 Pittsylvania Orders 40, reciting that, "Lodowick Tuggle, Gent., produced his commission as a Lieutenant in the Militia and took the oath by law prescribed."

On 18 June 1787 he filed his commission form the Governor and qualified as a Captain of the Pittsylvania Militia, (5 Pitt. Orders 494). He was still a Captain in the Militia in 1789, as is shown by reference in 4 Calendar if Virginia State Papers 646.

He took an active part in the government of Pittsylvania County. On 21 Nov 1780, he was accepted as one of four sureties on a bond of thirty thousand pounds to Thomas Jefferson as Governor to insure the collectionof the county revenues by Crispin Shelton, (6 PE Orders 72). In 1782, he was one of five sureties on the official bond of Abraham Shelton, then Sheriff.

The Journal of the Council of the State of Virginia under date of 18 June 1783 recites that Lodowick Tuggle, Gentleman, was appointed to the Commission of the Peace and Oyer and Terminer for the County of Pittsylvania, (5 Pitt. Orders 6). He was one of the Commissioners that laid out the Town of Cooksburg in 1788, (12 Hening 659).

The Vestry Book of Cambden Parish disclosed that beginning in 1782 and for some years thereafter he was a Vestryman of that Parish, (63 Vestry Book of Cambden Parish 1767-1852)...
...A Middlesex Court Order states that "Lodowick Tuggle, Gent. married Dorothy Lee, Spinster, Oct 1, 1765" (7 Wm. & Mary Quarterly 192; 
Middlesex Marriages Records (1740-1854, pg 16). The witnesses were John George and John Stringer. Dorothy Lee, wife of Lodowick, b. 31 March 1749, was a daughter of George Lee (1715-1757) who was married, 4 Dec 1737, to Mary Buford. George Lee was a son of Charles Lee (1683-1720) whose wife was named Dorothy. The father of Charles was Thomas Lee whose wife was named Elizabeth. Charles Lee, a brother of Dorothy (Lee) Tuggle, was Sheriff of Middle sex County in 1783, (44 Va. Mag. of History & Biog. 75).

On 18 July 1791 Lodowick and Dorothy sold their plantation of 1100 acres in Pittsylvania (9 Pitt. Deeds 30), and with their four sons, and almost certainly their six daughters, migrated to Georgia and settled on Little River, a tributary of the Savannah, then in Wilkes County.

The Tax Digest of Georgia (Blair 1926) lists him as a resident of Wilkes in 1793, owning 469 acres and 14 slaves. His sons, George, Robert, and Thomas were listed by name only. The following year Oglethorpe County was created from Wilkes and his plantation was in the new county in northwest Georgia.

Lodowick had been baptized, reared and married in the Anglican Church and was a member of the Vestry of Cambden Parish in Pittsylvania, but became active in the Presbyterian Church, probably because there was no Episcopal Church in the Area. In a historical sketch of New Hope Church in Oglethorpe in the Southern Presbyterian (1787) it is stated: "The Rev. John Newton was installed by the Presbytery of South Carolina as pastor of Bethany and New Hope about 1788. It appears that Allen Leeper, Lodowick Tuggle, and William Appleby were the first Elders...At the first meeting of Hopewell Presbytery in 1797 there were three Elders present as appears from the first Minutes, Ezekiel Gilham, Jacob Darrah, and Lodowick Tuggle..."